SAIKOSAPONIN B2(RG)
Saikosaponin B2
CAS: 58316-41-9
Molecular Formula: C42H68O13
SAIKOSAPONIN B2(RG) - Names and Identifiers
| Name | Saikosaponin B2 |
| Synonyms | SAIKOSAPONIN B2 Saikosaponin B2 Saikosaponin BII Fluoro nitroaniline SAIKOSAPONIN B2(RG) Saikosaponin b2 std. SAIKOSAPONINB2STANDARD trihydroxyoleana-11,13(18)-dien-3-yl6-deoxy-3-O-β-D-glucopyranosyl- (3b,4a,16a)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl-6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside [(4R)-16α,23,28-Trihydroxy-11,12,13,18-tetradehydrooleanan-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside (3beta,16alpha)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside |
| CAS | 58316-41-9 |
| InChI | InChI=1/C42H68O13/c1-21-29(47)34(55-35-32(50)31(49)30(48)24(18-43)53-35)33(51)36(52-21)54-28-11-12-38(4)25(39(28,5)19-44)10-13-40(6)26(38)9-8-22-23-16-37(2,3)14-15-42(23,20-45)27(46)17-41(22,40)7/h8-9,21,24-36,43-51H,10-20H2,1-7H3/t21-,24-,25-,26-,27-,28+,29+,30-,31+,32-,33-,34+,35+,36+,38+,39+,40-,41-,42-/m1/s1 |
SAIKOSAPONIN B2(RG) - Physico-chemical Properties
| Molecular Formula | C42H68O13 |
| Molar Mass | 780.99 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Melting Point | 231-238°C |
| Boling Point | 909.9±65.0 °C(Predicted) |
| Specific Rotation(α) | -11.5 º (c=1.0 g/100ml) |
| Flash Point | 504.075°C |
| Solubility | Soluble in methanol, pyridine, DMSO and other solvents, insoluble in petroleum ether. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White crystal |
| pKa | 12.83±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.619 |
| MDL | MFCD00210366 |
| Physical and Chemical Properties | alpha:-11.5 o (c=1.0 g/100ml) |
SAIKOSAPONIN B2(RG) - Reference
| Reference Show more | 1. Liu Shuqiang, Wang Zhuling, Gao Xiaoling, etc. Changes of saponins in the process of decoction of Bupleurum chinense [J]. Chinese new drugs and clinical pharmacology, 2013, 24(006):602-606. 2. Min Yuhang, Wang Jinhui, fan miaoxuan, etc. Study on changes of saponins and quality control of Bupleurum chinense decoction pieces [J]. Journal of Pharmaceutical Analysis, 2014, 034(005):836-843. 3. Xia Yanming, Dong Ying, Di Liuqing, etc. Simultaneous determination of four saikosaponins in Xiaozheng pellets by one-Test multi-evaluation method [J]. Chinese traditional medicines, 2017, 39(008):1620-1625. 4. Wei Yajie, Zhang Zekun, Guan Yanling, etc. Hugan Pian HPLC fingerprint and multi-component quantitative analysis [J]. Central South Pharmaceutical Journal, 2018, 016(001):31-34. 5. Feng Wenming, Sha Yi Wei, Zhou Dandan. Study on TLC identification of xiaochaihu granules [J]. China pharmaceuticals, 2020,29(23):46-49. 6. Han, C. H. E. N., et al. "Chemical profile of the active fraction of Yi-Gan San by HPLC-DAD-Q-TOF-MS and its neuroprotective effect against glutamate-induced cytotoxicity." Chinese journal of natural medicines 12.11 (2014): 869-880.https://doi.org/10.1016/ 7. [IF=3] Han CHEN et al."Chemical profile of the active fraction of Yi-Gan San by HPLC-DAD-Q-TOF-MS and its neuroprotective effect against glutamate-induced cytotoxicity."Chin J Nat Medicines. 2014 Nov;12:869 |
SAIKOSAPONIN B2(RG) - Reference Information
| introduction | saikosaponin B2 is saikosaponin B2, a white needle-like crystal with a molecular formula of C42H68O13 and a molecular weight of 780.99. it is the conversion component of saikosaponin d in saikurum. It has good anti-inflammatory, anti-tumor, antiviral and immunosuppressive pharmacological effects. |
| apply | saikosaponin B2 to prevent or treat renal fibrosis. Saikosaponin B2 includes the following applications: a1: preparation of drugs to prevent and/or treat renal tissue fibrosis; a2: prevention and/or treatment of renal tissue fibrosis; a3: inhibition of Hedgehog signaling pathway; a4: establishment of an animal medical model of renal tissue fibrosis. |
| biological activity | Saikosaponin B2 is an active ingredient isolated from Bupleurum root and is an invasion inhibitor of HCV virus infection. Anti-cancer effect. |
| chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Bupleurum. |
| use | saikosaponin B2 has anti-infection, anti-allergy, anti-virus and anti-shock effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: This product has the effects of dispersing wind and relieving fever, soothing the liver and relieving depression, and has certain prevention and treatment effects on colds and fever. |
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: Saikosaponin B2 Visit Supplier Webpage Request for quotationCAS: 58316-41-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Saikosaponin B2 Visit Supplier Webpage Request for quotationCAS: 58316-41-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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